Michael J Jurczak Selected Research

2,4-dinitrophenol methyl ether

11/2013

Reversal of hypertriglyceridemia, fatty liver disease, and insulin resistance by a liver-targeted mitochondrial uncoupler.

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Michael J Jurczak Research Topics

Disease

47	Insulin Resistance 01/2022 - 03/2009
20	Obesity 01/2022 - 03/2011
14	Type 2 Diabetes Mellitus (MODY) 01/2022 - 03/2011
10	Inflammation (Inflammations) 01/2021 - 04/2011
9	Weight Gain 01/2019 - 03/2007
8	Non-alcoholic Fatty Liver Disease 11/2016 - 03/2009
6	Body Weight (Weight, Body) 01/2022 - 03/2013
5	Hyperglycemia 01/2022 - 03/2011
4	Metabolic Syndrome (Dysmetabolic Syndrome X) 10/2019 - 02/2012
3	Glucose Intolerance 01/2022 - 03/2011
3	Sepsis (Septicemia) 01/2020 - 10/2019
3	Hyperinsulinism (Hyperinsulinemia) 01/2018 - 07/2014
3	Weight Loss (Weight Reduction) 01/2018 - 07/2010
3	Fatty Liver 01/2018 - 11/2013
3	Hypertriglyceridemia 01/2017 - 03/2009
3	Neoplasms (Cancer) 12/2014 - 04/2011
2	Diabetic Cardiomyopathies 01/2022 - 01/2019
2	Pneumonia (Pneumonitis) 01/2020 - 10/2019
2	Critical Illness (Critically Ill) 01/2020 - 11/2019
2	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2020 - 10/2019
2	Metabolic Diseases (Metabolic Disease) 10/2019 - 02/2016
2	Necrosis 01/2019 - 02/2012
2	Hypoxia (Hypoxemia) 01/2018 - 05/2015
1	Heart Failure 01/2022
1	Hypertrophy 01/2022
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2022
1	Wounds and Injuries (Trauma) 01/2021
1	Fibrosis (Cirrhosis) 11/2020
1	Cytokine Release Syndrome 01/2020
1	Systemic Scleroderma (Systemic Sclerosis) 01/2020
1	Lung Injury 01/2020
1	Cystic Fibrosis (Mucoviscidosis) 01/2020
1	Hypoglycemia (Reactive Hypoglycemia) 11/2019
1	Dyslipidemias (Dyslipidemia) 01/2019
1	Cardiomyopathies (Cardiomyopathy) 01/2019
1	Hyperuricemia 01/2019
1	Liver Diseases (Liver Disease) 01/2019
1	Maternal Obesity 01/2018

Drug/Important Bio-Agent (IBA)

28	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 11/2010
23	LipidsIBA 01/2022 - 12/2010
23	Insulin (Novolin)FDA Link 11/2019 - 03/2009
10	DiglyceridesIBA 11/2019 - 11/2010
7	Fatty Acids (Saturated Fatty Acids)IBA 01/2022 - 07/2013
7	CytokinesIBA 01/2021 - 11/2011
6	CeramidesIBA 11/2019 - 04/2011
4	Reactive Oxygen Species (Oxygen Radicals)IBA 10/2019 - 11/2014
4	EnzymesIBA 10/2019 - 01/2012
4	fibroblast growth factor 21IBA 01/2019 - 09/2013
4	Triglycerides (Triacylglycerol)IBA 02/2017 - 07/2010
4	Antisense OligonucleotidesIBA 03/2016 - 01/2013
3	SodiumIBA 01/2022 - 10/2016
3	Proteins (Proteins, Gene)FDA Link 01/2020 - 01/2012
3	Blood Glucose (Blood Sugar)IBA 01/2019 - 12/2012
3	Phosphotransferases (Kinase)IBA 01/2018 - 04/2011
3	Insulin ReceptorIBA 11/2016 - 11/2011
3	Tyrosine (L-Tyrosine)FDA Link 01/2012 - 11/2010
2	SymportersIBA 01/2022 - 01/2018
2	RNA (Ribonucleic Acid)IBA 11/2020 - 01/2019
2	Protein Isoforms (Isoforms)IBA 10/2019 - 10/2013
2	Oxidoreductases (Dehydrogenase)IBA 10/2019 - 11/2014
2	Estradiol (Delestrogen)FDA LinkGeneric 01/2019 - 03/2013
2	Interleukin-6 (Interleukin 6)IBA 01/2019 - 01/2015
2	Growth Hormone (Somatotropin)IBA 01/2018 - 01/2017
2	Inositol (Myoinositol)IBA 02/2017 - 01/2012
2	Uncoupling AgentsIBA 01/2017 - 11/2013
2	CatalaseIBA 01/2017 - 12/2010
2	Protein Kinase CIBA 11/2016 - 11/2011
2	InflammasomesIBA 12/2015 - 02/2012
2	Acetyl Coenzyme A (Acetyl-CoA)IBA 02/2015 - 11/2014
2	Interleukin-18 (Interleukin 18)IBA 03/2013 - 02/2012
2	Protein Kinases (Protein Kinase)IBA 02/2012 - 04/2011
2	Insulin Receptor Substrate ProteinsIBA 04/2011 - 11/2010
1	XenobioticsIBA 01/2022
1	Constitutive Androstane ReceptorIBA 01/2022
1	Benzene (Benzole)IBA 01/2022
1	Sodium-Glucose Transporter 2 InhibitorsIBA 01/2022
1	3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-oneIBA 01/2021
1	Interleukin-10 (Interleukin 10)IBA 01/2021
1	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 01/2020
1	UbiquitinIBA 01/2020
1	Interleukin-3 (Interleukin 3)IBA 01/2020
1	Glucagon-Like Peptide 1 (GLP 1)IBA 11/2019
1	Peptides (Polypeptides)IBA 11/2019
1	Therapeutic UsesIBA 11/2019
1	Hormones (Hormone)IBA 11/2019
1	IncretinsIBA 11/2019
1	NADP (NADPH)IBA 10/2019
1	NADPH Oxidases (NAD(P)H oxidase)IBA 10/2019
1	Liver GlycogenIBA 01/2019
1	Biomarkers (Surrogate Marker)IBA 01/2019
1	GlucocorticoidsIBA 01/2019
1	Xanthine DehydrogenaseIBA 01/2019
1	Uric Acid (Urate)IBA 01/2019
1	Febuxostat FDA Link 01/2019
1	Mediator ComplexIBA 01/2019
1	Transcription Factors (Transcription Factor)IBA 01/2019
1	p38 Mitogen-Activated Protein KinasesIBA 01/2018

Therapy/Procedure

8	Therapeutics 01/2022 - 09/2013
2	Glycemic Control 11/2019 - 01/2018
2	Ketogenic Diet 09/2015 - 11/2010